Alx Oncology Holdings IncAlx Oncology Holdings Inc
Alx Oncology Holdings Inc

Alx Oncology Holdings Inc

ALXO
Health Care·Biotechnology

ALX Oncology Holdings, Inc. is a clinical-stage biotechnology company, which engages in the research and development of therapies for cancer patients. Its objective is to provide clinical therapies for the treatment of myelodysplastic syndromes, acute myeloid leukemia, and a range of solid tumor indications. The company was founded by Corey Goodman, Jaume Pons, and K. Christopher Garcia in March 2015 and is headquartered in South San Francisco, CA.

California; U.S.A
Market cap
No dataNo data
Revenue
No dataNo data
Net income
$-101.7M+24.6% YoY
Free cash flow
$-84.4M+31.1% YoY

Market

Listed stock
ALXOPriceNasdaq
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Financial performance

Revenue
No dataNo data
Operating income
$-104M+27.0% YoY
Net income
$-101.7M+24.6% YoY
Free cash flow
$-84.4M+31.1% YoY

Revenue, profit & cash trend

Revenue
Reference
Revenue: 2021 $1.2M, 2022 $0, 2023 $0, 2024 $0. Reference line: Reference at $0.

Growth & profitability

Revenue growth
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Gross margin
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Operating margin
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FCF margin
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Earnings power over time

Operating income
Net income
Free cash flow
Operating income: 2021-12-31 $-83.6M, 2022-12-31 $-127.4M, 2023-12-31 $-170.3M, 2024-12-31 $-142.5M, 2025-12-31 $-104M. Net income: 2021-12-31 $-83.5M, 2022-12-31 $-123.5M, 2023-12-31 $-160.8M, 2024-12-31 $-134.9M, 2025-12-31 $-101.7M. Free cash flow: 2021-12-31 $-68.8M, 2022-12-31 $-90.7M, 2023-12-31 $-131.6M, 2024-12-31 $-122.4M, 2025-12-31 $-84.4M

Growth heatmap

202220232024CAGR
Revenue
-100.0%
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Gross profit
-66.8%
+100.0%
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No data
Operating income
-52.5%
-33.6%
+16.3%
+27.0%
No data
Free cash flow
-31.8%
-45.2%
+7.0%
+31.1%
No data

Earnings quality

Operating cash flow
$-84.1M+31.0% YoY
Net income
$-101.7M+24.6% YoY
Free cash flow
$-84.4M+31.1% YoY
Diluted EPS
No dataNo data

Cash conversion quality

Operating cash flow
Free cash flow
Net income = 100%
Operating cash flow: 2025-12-31 83%, 2024-12-31 90%, 2023-12-31 81%, 2022-12-31 72%, 2021-12-31 82%. Free cash flow: 2025-12-31 83%, 2024-12-31 91%, 2023-12-31 82%, 2022-12-31 73%, 2021-12-31 82%. Reference line: Net income = 100% at 100%.

Per-share economics

Diluted EPS
Latest
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FCF / share
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Diluted shares
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Financial flexibility

Cash & equivalents
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Total debt
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Net debt
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Current ratio
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Cash Coverage of Debt

Cash / Total debt
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Returns

Return on equity
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Return on assets
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Return on invested capital
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Asset turnover
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Return on capital

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Valuation

Price to earnings
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Price to sales
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EV / EBITDA
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Free cash flow yield
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Valuation vs its own 5Y history

Metric
Own five-year range
Current
Own 5Y median
Position in own range
Price to earnings
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Price to sales
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EV / EBITDA
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Free cash flow yield
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