Annovis Bio IncAnnovis Bio Inc
Annovis Bio Inc

Annovis Bio Inc

ANVS
Health Care·Biotechnology

Annovis Bio, Inc. is a clinical stage drug platform company, which engages in the development of drugs aiming to treat neurodegenerative diseases, such as Alzheimer's (AD) and Parkinson's (PD). Its lead product candidate, Buntanetap, is designed to address AD, PD, and potentially other chronic neurodegenerative diseases. The company's product pipeline also includes ANVS405 and ANVS301, which focus on the treatment of traumatic brain injury, stroke, and advanced AD. Annovis Bio was founded by Maria Luisa Maccecchini in May 2008 and is headquartered in Malvern, PA.

Pennsylvania; U.S.A
Market cap
$50.3MNo data
Revenue
$0No data
Net income
No dataNo data
Free cash flow
$-25.6M−17.0% YoY

Market

Listed stock
ANVSPriceNYSE
Loading…Loading…1Y

Financial performance

Revenue
$0No data
Operating income
$-29.7M−11.2% YoY
Net income
No dataNo data
Free cash flow
$-25.6M−17.0% YoY

Revenue, profit & cash trend

Revenue
Operating income
Free cash flow
Reference
Revenue: 2021 $0, 2022 $0, 2023 $0, 2024 $0, 2025 $0. Operating income: 2021 $-14.5M, 2022 $-25.5M, 2023 $-45M, 2024 $-26.7M, 2025 $-29.7M. Free cash flow: 2021 $-9.1M, 2022 $-17.3M, 2023 $-40M, 2024 $-21.9M, 2025 $-25.6M. Reference line: Reference at $0.

Growth & profitability

Revenue growth
No dataNo data
Gross margin
No dataNo data
Operating margin
No dataNo data
FCF margin
No dataNo data

Earnings power over time

Operating income
Free cash flow
Operating income: 2021-12-31 $-14.5M, 2022-12-31 $-25.5M, 2023-12-31 $-45M, 2024-12-31 $-26.7M, 2025-12-31 $-29.7M. Free cash flow: 2021-12-31 $-9.1M, 2022-12-31 $-17.3M, 2023-12-31 $-40M, 2024-12-31 $-21.9M, 2025-12-31 $-25.6M

Growth heatmap

2022202320242025CAGR
Revenue
No data
No data
No data
No data
No data
Gross profitNo data
No data
Operating income
-75.5%
-76.5%
+40.7%
-11.2%
No data
Free cash flow
-89.6%
-130.9%
+45.2%
-17.0%
No data

Earnings quality

Operating cash flow
$-25.6M−17.0% YoY
Net income
No dataNo data
Free cash flow
$-25.6M−17.0% YoY
Diluted EPS
No dataNo data

Cash conversion quality

No data

Per-share economics

Diluted EPS
Latest
No data
FCF / share
Latest
No data
Diluted shares
Latest
No data

Financial flexibility

Cash & equivalents
No dataNo data
Total debt
No dataNo data
Net debt
No dataNo data
Current ratio
No dataNo data

Cash Coverage of Debt

Cash / Total debt
No data

Returns

Return on equity
No dataNo data
Return on assets
No dataNo data
Return on invested capital
No dataNo data
Asset turnover
No dataNo data

Return on capital

No data

Valuation

Price to earnings
No dataNo data
Price to sales
No dataNo data
EV / EBITDA
No dataNo data
Free cash flow yield
No dataNo data

Valuation vs its own 5Y history

Metric
Own five-year range
Current
Own 5Y median
Position in own range
Price to earnings
No data
No data
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Price to sales
No data
No data
No data
No data
EV / EBITDA
No data
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No data
Free cash flow yield
No data
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No data
No data