Aptevo Therapeutics IncAptevo Therapeutics Inc
Aptevo Therapeutics Inc

Aptevo Therapeutics Inc

APVO
Health Care·Biotechnology

Aptevo Therapeutics, Inc. is a clinical-stage biotechnology company, which engages on developing novel immunotherapies for the treatment of cancer. Its pipeline APVO436, ALG.APV-527, and APVO603 were developed based on the ADAPTIR modular protein platform technology and APVO442 was developed based on the new ADAPTIR-FLE platform technology. The ADAPTIR and ADAPTIR-FLEX are capable of generating differentiated bispecific and multi-specific antibodies with potentially unique mechanisms of action for the treatment of different types of cancer. The company was founded in February 2016 and is headquartered in Seattle, WA.

Washington; U.S.A
Market cap
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Revenue
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Net income
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Free cash flow
$-25.6M−7.6% YoY

Market

Listed stock
APVOPriceNasdaq
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Financial performance

Revenue
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Operating income
$-26.3M−7.0% YoY
Net income
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Free cash flow
$-25.6M−7.6% YoY

Revenue, profit & cash trend

Revenue
Reference
Revenue: 2021 $12.3M, 2022 $3.1M, 2023 $3.1M, 2024 $0. Reference line: Reference at $0.

Growth & profitability

Revenue growth
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Gross margin
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Operating margin
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FCF margin
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Earnings power over time

Operating income
Free cash flow
Operating income: 2021-12-31 $-21.4M, 2022-12-31 $-28.6M, 2023-12-31 $-28.9M, 2024-12-31 $-24.6M, 2025-12-31 $-26.3M. Free cash flow: 2021-12-31 $-22.4M, 2022-12-31 $-21.1M, 2023-12-31 $-11.8M, 2024-12-31 $-23.8M, 2025-12-31 $-25.6M

Growth heatmap

202220232024CAGR
Revenue
-74.7%
0.0%
-100.0%
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Gross profitNo data
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Operating income
-33.8%
-0.8%
+14.8%
-7.0%
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Free cash flow
+6.0%
+44.1%
-102.3%
-7.6%
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Earnings quality

Operating cash flow
$-25.6M−7.6% YoY
Net income
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Free cash flow
$-25.6M−7.6% YoY
Diluted EPS
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Cash conversion quality

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Per-share economics

Diluted EPS
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FCF / share
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Diluted shares
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Financial flexibility

Cash & equivalents
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Total debt
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Net debt
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Current ratio
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Cash Coverage of Debt

Cash / Total debt
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Returns

Return on equity
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Return on assets
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Return on invested capital
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Asset turnover
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Return on capital

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Valuation

Price to earnings
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Price to sales
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EV / EBITDA
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Free cash flow yield
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Valuation vs its own 5Y history

Metric
Own five-year range
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Position in own range
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Price to sales
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EV / EBITDA
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Free cash flow yield
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