Biomea Fusion IncBiomea Fusion Inc
Biomea Fusion Inc

Biomea Fusion Inc

BMEA
Health Care·Biotechnology

Biomea Fusion, Inc. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of covalent small molecule drugs to treat patients with genetically defined cancers and metabolic disorders, such as diabetes. It offers its lead product candidate, BMF-219, an orally bioavailable, potent, and selective covalent inhibitor of menin, a transcriptional regulator known to play a direct role in oncogenic signaling in multiple cancers. The company was founded by Thomas Butler and Ramses Erdtmann in August 2017 and is headquartered in San Carlos, CA.

California; U.S.A
Market cap
No dataNo data
Revenue
No dataNo data
Net income
$-61.8M+55.4% YoY
Free cash flow
$-70.7M+41.2% YoY

Market

Listed stock
BMEAPriceNasdaq
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Financial performance

Revenue
No dataNo data
Operating income
$-83.5M+42.0% YoY
Net income
$-61.8M+55.4% YoY
Free cash flow
$-70.7M+41.2% YoY

Revenue, profit & cash trend

Revenue
Reference
Revenue: 2021 $0, 2022 $0, 2023 $0, 2024 $0. Reference line: Reference at $0.

Growth & profitability

Revenue growth
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Gross margin
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Operating margin
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FCF margin
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Earnings power over time

Operating income
Net income
Free cash flow
Operating income: 2021-12-31 $-41.7M, 2022-12-31 $-83.6M, 2023-12-31 $-126.1M, 2024-12-31 $-144.1M, 2025-12-31 $-83.5M. Net income: 2021-12-31 $-41.6M, 2022-12-31 $-81.8M, 2023-12-31 $-117.3M, 2024-12-31 $-138.4M, 2025-12-31 $-61.8M. Free cash flow: 2021-12-31 $-38.6M, 2022-12-31 $-63.4M, 2023-12-31 $-100M, 2024-12-31 $-120.3M, 2025-12-31 $-70.7M

Growth heatmap

202220232024CAGR
Revenue
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Gross profit
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Operating income
-100.7%
-50.8%
-14.2%
+42.0%
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Free cash flow
-64.3%
-57.6%
-20.3%
+41.2%
No data

Earnings quality

Operating cash flow
$-70.4M+41.3% YoY
Net income
$-61.8M+55.4% YoY
Free cash flow
$-70.7M+41.2% YoY
Diluted EPS
No dataNo data

Cash conversion quality

Operating cash flow
Free cash flow
Net income = 100%
Operating cash flow: 2025-12-31 114%, 2024-12-31 87%, 2023-12-31 82%, 2022-12-31 76%, 2021-12-31 85%. Free cash flow: 2025-12-31 114%, 2024-12-31 87%, 2023-12-31 85%, 2022-12-31 78%, 2021-12-31 93%. Reference line: Net income = 100% at 100%.

Per-share economics

Diluted EPS
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FCF / share
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Diluted shares
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Financial flexibility

Cash & equivalents
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Total debt
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Net debt
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Current ratio
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Cash Coverage of Debt

Cash / Total debt
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Returns

Return on equity
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Return on assets
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Return on invested capital
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Asset turnover
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Return on capital

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Valuation

Price to earnings
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Price to sales
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EV / EBITDA
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Free cash flow yield
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Valuation vs its own 5Y history

Metric
Own five-year range
Current
Own 5Y median
Position in own range
Price to earnings
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Price to sales
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EV / EBITDA
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Free cash flow yield
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