Design Therapeutics IncDesign Therapeutics Inc
Design Therapeutics Inc

Design Therapeutics Inc

DSGN
Health Care·Biotechnology

Design Therapeutics, Inc. operates as a biotechnology company that develops therapies for serious degenerative disorders. It is created to design, develop and commercialize a novel class of small molecule therapeutic candidates (GeneTACs) designed to directly address the underlying basis of genetic disease. The company was founded by Pratik Shah and Aseem Z. Ansari on December 18, 2017 and is headquartered in Carlsbad, CA.

California; U.S.A
Market cap
$719.1MNo data
Revenue
$0No data
Net income
$-69.8M−40.7% YoY
Free cash flow
$-54.6M−25.6% YoY

Market

Listed stock
DSGNPriceNasdaq
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Financial performance

Revenue
$0No data
Operating income
$-79.5M−27.4% YoY
Net income
$-69.8M−40.7% YoY
Free cash flow
$-54.6M−25.6% YoY

Revenue, profit & cash trend

Revenue
Operating income
Net income
Free cash flow
Reference
Revenue: 2021 $226K, 2022 $0, 2023 $0, 2024 $0, 2025 $0. Operating income: 2021 $-35.8M, 2022 $-67.6M, 2023 $-78.2M, 2024 $-62.4M, 2025 $-79.5M. Net income: 2021 $-35.5M, 2022 $-63.3M, 2023 $-66.9M, 2024 $-49.6M, 2025 $-69.8M. Free cash flow: 2021 $-30.9M, 2022 $-52.2M, 2023 $-58.8M, 2024 $-43.4M, 2025 $-54.6M. Reference line: Reference at $0.

Growth & profitability

Revenue growth
No dataNo data
Gross margin
No dataNo data
Operating margin
No dataNo data
FCF margin
No dataNo data

Earnings power over time

Operating income
Net income
Free cash flow
Operating income: 2021-12-31 $-35.8M, 2022-12-31 $-67.6M, 2023-12-31 $-78.2M, 2024-12-31 $-62.4M, 2025-12-31 $-79.5M. Net income: 2021-12-31 $-35.5M, 2022-12-31 $-63.3M, 2023-12-31 $-66.9M, 2024-12-31 $-49.6M, 2025-12-31 $-69.8M. Free cash flow: 2021-12-31 $-30.9M, 2022-12-31 $-52.2M, 2023-12-31 $-58.8M, 2024-12-31 $-43.4M, 2025-12-31 $-54.6M

Growth heatmap

2022202320242025CAGR
Revenue
-100.0%
No data
No data
No data
No data
Gross profit
+100.0%
No data
No data
No data
No data
Operating income
-88.6%
-15.7%
+20.2%
-27.4%
No data
Free cash flow
-69.0%
-12.6%
+26.1%
-25.6%
No data

Earnings quality

Operating cash flow
$-54.4M−26.1% YoY
Net income
$-69.8M−40.7% YoY
Free cash flow
$-54.6M−25.6% YoY
Diluted EPS
No dataNo data

Cash conversion quality

Operating cash flow
Free cash flow
Net income = 100%
Operating cash flow: 2025-12-31 78%, 2024-12-31 87%, 2023-12-31 88%, 2022-12-31 81%, 2021-12-31 83%. Free cash flow: 2025-12-31 78%, 2024-12-31 88%, 2023-12-31 88%, 2022-12-31 83%, 2021-12-31 87%. Reference line: Net income = 100% at 100%.

Per-share economics

Diluted EPS
Latest
No data
FCF / share
Latest
No data
Diluted shares
Latest
No data

Financial flexibility

Cash & equivalents
No dataNo data
Total debt
No dataNo data
Net debt
No dataNo data
Current ratio
No dataNo data

Cash Coverage of Debt

Cash / Total debt
No data

Returns

Return on equity
No dataNo data
Return on assets
No dataNo data
Return on invested capital
No dataNo data
Asset turnover
No dataNo data

Return on capital

No data

Valuation

Price to earnings
No dataNo data
Price to sales
No dataNo data
EV / EBITDA
No dataNo data
Free cash flow yield
No dataNo data

Valuation vs its own 5Y history

Metric
Own five-year range
Current
Own 5Y median
Position in own range
Price to earnings
No data
No data
No data
No data
Price to sales
No data
No data
No data
No data
EV / EBITDA
No data
No data
No data
No data
Free cash flow yield
No data
No data
No data
No data