Lexeo Therapeutics IncLexeo Therapeutics Inc
Lexeo Therapeutics Inc

Lexeo Therapeutics Inc

LXEO
Health Care·Biotechnology

Lexeo Therapeutics, Inc. is a clinical stage genetic medicine company, which engages in the development of therapies for hereditary and acquired diseases. The firm focuses on the medication of genetically defined cardiovascular diseases and sub-group of Alzheimer’s disease. It offers LX2006 for the treatment of patients with Friedreich's ataxia, cardiomyopathy, and LX1001 for APOE4 homozygous patients with Alzheimer's disease. The company was founded by Ronald G. Crystal in February 2017 and is headquartered in New York, NY.

New York; U.S.A
Market cap
No dataNo data
Revenue
No dataNo data
Net income
$-100M−1.7% YoY
Free cash flow
$-99M−21.2% YoY

Market

Listed stock
LXEOPriceNasdaq
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Financial performance

Revenue
No dataNo data
Operating income
$-109.3M−3.3% YoY
Net income
$-100M−1.7% YoY
Free cash flow
$-99M−21.2% YoY

Revenue, profit & cash trend

Revenue
Reference
Revenue: 2021 $1.7M, 2022 $654K, 2023 $654K, 2024 $0. Reference line: Reference at $0.

Growth & profitability

Revenue growth
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Gross margin
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Operating margin
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FCF margin
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Earnings power over time

Operating income
Net income
Free cash flow
Operating income: 2021-12-31 $-50.6M, 2022-12-31 $-60.5M, 2023-12-31 $-68.5M, 2024-12-31 $-105.8M, 2025-12-31 $-109.3M. Net income: 2021-12-31 $-50.6M, 2022-12-31 $-59.3M, 2023-12-31 $-66.4M, 2024-12-31 $-98.3M, 2025-12-31 $-100M. Free cash flow: 2021-12-31 $-44.4M, 2022-12-31 $-55.2M, 2023-12-31 $-59.6M, 2024-12-31 $-81.6M, 2025-12-31 $-99M

Growth heatmap

202220232024CAGR
Revenue
-60.5%
0.0%
-100.0%
No data
Gross profit
-60.5%
-8165.3%
+100.0%
No data
Operating income
-19.5%
-13.2%
-54.4%
-3.3%
No data
Free cash flow
-24.5%
-7.9%
-36.9%
-21.2%
No data

Earnings quality

Operating cash flow
$-98.6M−21.5% YoY
Net income
$-100M−1.7% YoY
Free cash flow
$-99M−21.2% YoY
Diluted EPS
No dataNo data

Cash conversion quality

Operating cash flow
Free cash flow
Net income = 100%
Operating cash flow: 2025-12-31 99%, 2024-12-31 83%, 2023-12-31 90%, 2022-12-31 92%, 2021-12-31 87%. Free cash flow: 2025-12-31 99%, 2024-12-31 83%, 2023-12-31 90%, 2022-12-31 93%, 2021-12-31 88%. Reference line: Net income = 100% at 100%.

Per-share economics

Diluted EPS
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FCF / share
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Diluted shares
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Financial flexibility

Cash & equivalents
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Total debt
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Net debt
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Current ratio
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Cash Coverage of Debt

Cash / Total debt
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Returns

Return on equity
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Return on assets
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Return on invested capital
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Asset turnover
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Return on capital

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Valuation

Price to earnings
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Price to sales
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EV / EBITDA
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Free cash flow yield
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Valuation vs its own 5Y history

Metric
Own five-year range
Current
Own 5Y median
Position in own range
Price to earnings
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Price to sales
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EV / EBITDA
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Free cash flow yield
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